近年来,用cDNA克隆和mRNA表达分析表明,Na,K-ATP酶的催化亚基至少存在3种亚型,即α_1,α_2、α_3亚型。以这些亚型的特异性cDNA探针检测组织,发现红细胞和肾脏均为α_1亚型。而其它组织如大脑则含有全部3种亚型。由于成熟红细胞和网织红细胞缺乏Na,K-ATP酶mRNA,故作者 In recent years, cDNA cloning and mRNA expression analysis showed that there are at least three subtypes of catalytic subunits of Na and K-ATPase, namely α_1, α_2 and α_3 subtypes. With these subtypes of specific cDNA probe detection of tissue and found that red blood cells and kidneys were α_1 subtype. Other tissues such as the brain contain all three subtypes. Because of the lack of mature erythrocytes and reticulocytes Na, K-ATPase mRNA, so the author