本文就肺部孤立性结节的临床、X线、活检及其倍增时间等问题阐述其处理原则。标准处理近20年来对于肺部孤立性结节病灶的文献有如下的观点:(1)切除的孤立性结节中约15～50％属原发性或转移性恶性肿瘤。(2)结节内呈现广泛钙化或经过二年以上无增大者很可能是良性结节。但很多良性结节没有钙化, In this paper, the principle of the treatment of solitary nodules in the lung is described in terms of clinical, X-ray, biopsy, and doubling time. The standard treatment of isolated solitary nodular lesions in the lung for the past 20 years has the following observations: (1) About 15 to 50% of isolated solitary nodules are primary or metastatic. (2) The presence of extensive calcification within the nodule or no increase after more than two years is likely to be a benign nodule. However, many benign nodules do not calcify.