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目的了解用阿奇霉素对肺炎患儿进行治疗的病情干预效果和药物安全性。方法 :一般资料来自本院2013-2016年期间收治并确诊为肺炎患儿的相关临床数据,从中随机抽取60例并根据患儿所接受对应治疗方案将其每组30例分为对照组、观察组,其治疗方案分别为常规对症干预联合红霉素、常规对症治疗联合阿奇霉素治疗干预,在完成疗程后比较阿奇霉素对小儿肺炎病情改善效果及药物安全性。结果根据患儿病情状况作为疗效判断依据,提示观察组总有效率明显高于对照组并通过统计学对组间差异处理后表示有意义(P<0.05);疗程及随访期间对照组患儿发生不良反应例数4例,观察组未发现有不良反应情况,组间统计学处理提示有意义(P<0.05)。结论肺炎患儿用阿奇霉素治疗相对于传统红霉素药物能在更短时间内平缓其病情,有良好治疗效果且安全性高,值得推广。
Objective To understand the therapeutic effect of azithromycin on children with pneumonia and drug safety. Methods: The general data were from our hospital from 2013 to 2016 admitted and diagnosed as pneumonia in children with relevant clinical data, 60 patients were randomly selected and treated according to the treatment of children received each of the 30 cases were divided into control group, observed Group, the treatment regimens were routine symptomatic intervention combined with erythromycin, conventional symptomatic treatment combined with azithromycin treatment intervention, azithromycin in children after treatment to improve the effect of pneumonia and drug safety. Results According to children’s condition as the basis of curative effect, the total effective rate of the observation group was significantly higher than that of the control group and statistically significant difference (P <0.05); during the treatment and follow-up period in the control group Adverse reactions in 4 cases, the observation group did not find any adverse reactions, statistical analysis showed significant (P <0.05). Conclusion The treatment of azithromycin in children with pneumonia compared with the traditional erythromycin drugs in a relatively short period of time to ease their condition, with good therapeutic effect and high safety, it is worth promoting.