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尤文氏肉瘤是一种预后极坏的恶性骨肿瘤,但近10年来由于采用多种药物的联合化疗,并对原发肿瘤进行放疗,其结果有了显著的改善。本文分析193例局限性尤文氏肉瘤,随机分成3组,第一组73例用VAC(长春新碱、放线菌素、D 和环磷酰胺)加阿霉素治疗,第二组64例单用VAC,第三组56例用VAC 化疗并对全肺作预防性照射。三组的平均随访期分别为64周、86周102周。每一例都对原发肿瘤进行高能X 线治疗,受侵骨骼全部照射,肿瘤达4600～500rad 后,在病灶边缘5公分范围内
Ewing’s sarcoma is a malignant bone tumor with a very poor prognosis. However, in the past 10 years, the use of multiple drugs in combination with chemotherapy and radiotherapy of primary tumors has significantly improved the results. This article analyzed 193 cases of localized Ewing’s sarcoma and randomly divided into 3 groups. The first group of 73 cases were treated with VAC (vincristine, actinomycin, D, and cyclophosphamide) plus adriamycin, and the second group of 64 cases. With VAC, the third group of 56 patients received VAC chemotherapy and prophylactic irradiation to the whole lung. The average follow-up period for the three groups was 64 weeks and 86 weeks and 102 weeks, respectively. In each case, the primary tumors were treated with high-energy X-rays. All affected bones were irradiated. After the tumor reached 4,600 to 500 rad, within 5 cm of the edge of the lesion.