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用动物实验方法,研究地胆根乙醇提取液治疗支气管炎,咳、痰、喘三种症状的效果及其药理作用.给豚鼠腹腔泣射地胆根乙醇提取液,能显著地增大方波刺激迷走神经的引咳阈值;给小白鼠灌胃,能非常显著增加其呼吸道的酚红排泌量;给豚鼠离体气管滴入提取液,对气管有非常显著的扩张效应;该提取液能延长豚鼠的引喘潜伏期,对蛙口腔粘膜上皮的纤毛运动有一定的加快作用.地胆根乙醇提取液有明显的镇咳、祛痰和平喘作用.
Animal experiment method was used to study the effect of ethanol extract of Radix Gambies on bronchitis, cough, sputum, and asthma and its pharmacological effects. The ethanol extract of biliary roots in the abdominal cavity of guinea pigs can significantly increase the square wave. Stimulate the coughing threshold of the vagus nerve; gavage the mouse, can significantly increase the respiratory phenol red excretion; Giving guinea pigs in vitro tracheal instillation extract, the trachea has a very significant expansion effect; the extract can extend The incubation period of guinea pigs has a certain role in accelerating the cilia movement in the oral mucosal epithelium of frogs. The ethanol extract of gentian root has obvious antitussive, expectorant and antiasthmatic effects.