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目的:探讨冠心病患者C反应蛋白(CRP)与胱抑素C(CysC)检测的临床价值。方法:选择冠心病106例,包括急性心肌梗死(AMI组)35例,不稳定型心绞痛(UA组)43例、稳定型心绞痛(SA组)28例;另选择健康体检者30例作为对照组。CRP检测采用乳胶凝集比浊法,CysC检测采用乳胶颗粒增强免疫透射比浊法。结果:CRP水平AMI组较对照组显著增高(P<0.01),UA组亦高于对照组(P<0.05),SA组与对照组比较,差异不显著(P>0.05)。CysC水平AMI组较对照组显著增高(P<0.01),UA组及SA组亦高于对照组(P<0.05)。结论:CRP与CysC水平检测对冠状动脉病变及其严重程度评定有重要参考价值。
Objective: To investigate the clinical value of C-reactive protein (CRP) and cystatin C (CysC) in patients with coronary heart disease. Methods: A total of 106 patients with coronary heart disease were selected, including 35 patients with acute myocardial infarction (AMI), 43 patients with unstable angina pectoris (UA) and 28 patients with stable angina (SA). Another 30 healthy subjects were selected as control group . CRP test using latex agglutination turbidimetric method, CysC detection using latex particle enhanced immunoturbidimetric method. Results: The level of CRP in AMI group was significantly higher than that in control group (P <0.01). The level of CRP in UA group was also higher than that in control group (P <0.05). There was no significant difference between SA group and control group (P> 0.05). The level of CysC in AMI group was significantly higher than that in control group (P <0.01), but also higher in UA group and SA group than in control group (P <0.05). Conclusion: The detection of CRP and CysC has important reference value for the evaluation of coronary artery disease and its severity.