1939年Friedrich首先报告一组肺癌,其发生与早先形成的肺部瘢痕紧密相关,称之为瘢痕癌。作者采用同一标准诊断瘢痕癌,这些标准即肿瘤位于肺的周边、无起源于支气管的证据并围绕真性透明性变的瘢痕组织发生,同时具有下列形态学特点:1)肿瘤表面的胸膜通常增厚并形成绉褶;2)在瘢痕中常有炭未色素沉着及提示胆固醇结晶蓄积的裂隙存在;3)在直接围绕瘢痕的肿瘤的中心常见坏死带,其内亦常见炭未色素和胆固醇裂隙。 1955——1975年21年中计有7629例尸检病例。不论患者生前是否诊断或怀疑肺癌、肺癌是否死亡直接原因以及肿瘤的大小,每一病例于尸检时均经过肺部病理检查。其中诊断肺癌者1186例,经复习发现 In 1939, Friedrich first reported a group of lung cancers. Their occurrence was closely related to the early formation of scars in the lungs. It was called scar cancer. The authors used the same criteria to diagnose scar cancer. These criteria were that the tumor was located on the periphery of the lung, there was no evidence of origin of the bronchus, and the scar tissue around the true transparency changed. It also had the following morphological features: 1) The pleura on the tumor surface was usually thickened And forming pleated folds; 2) often in the scars of carbon unpigmented and prompted the accumulation of cholesterol crystals cracks exist; 3) in the center of the tumor directly around the scar commonly necrotic zone, which is also common in carbon pigment and cholesterol cracks. In the period from 1955 to 1975, there were 7,629 autopsy cases. Regardless of whether the patient diagnosed or suspected lung cancer, the direct cause of death from lung cancer, and the size of the tumor, each patient had a lung pathology examination at the time of autopsy. 1186 cases of lung cancer were diagnosed and found through review