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椎管内肿瘤发生颅内压增高是少见的,从目前文献报告的45例中,普遍发现这些病例的脑脊液蛋白量(腰穿)均有显著增高。Gardner等认为颅内压增高是由于脑脊液蛋白量增高导致脑脊液吸收功能障碍的结果。本文报告2例伴有颅内压增高的椎管内肿瘤,通过对脑脊液蛋白和脑脊液吸收功能的研究分析支持了上述观点,分别采取切除肿瘤及作脑脊液分流术后使症状得到改善。例一,女性,61岁,病程1个月,有头痛呕吐,定向错误、意识障碍,眼底视乳头水肿等颅内压增高的症状及体征,而无其他定位体征而入院。脑室造影示所有脑室均扩大,四脑室向上移位。经手术
Intracranial tumors are rare in intracranial hypertension. From the current 45 cases reported in the literature, it is generally found that the CSF protein content (lumbar puncture) is significantly higher in these cases. Gardner et al. believe that the increase of intracranial pressure is due to the increase of cerebrospinal fluid protein levels leading to the dysfunction of cerebrospinal fluid absorption. This article reports two cases of intraspinal tumors with increased intracranial pressure. These findings were supported by analysis of cerebrospinal fluid protein and cerebrospinal fluid absorption. The symptoms were improved after the removal of tumors and cerebrospinal fluid shunting. Case 1, female, 61 years old, duration of 1 month, headache vomiting, misorientation, disturbance of consciousness, retinal papilledema and other symptoms and signs of increased intracranial pressure, and no other location signs were admitted to hospital. Ventricular angiography showed that all ventricles were enlarged and the fourth ventricle was shifted upward. After surgery