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众所周知,恶性肿瘤与凝血异常之间有各种各样的关系。对其成因的研究,已逐步有所进展。有关血液凝固,纤溶系统的血小板、血管内皮细胞对恶性肿瘤细胞的增殖、转移有重要的关系,特别是关于恶性肿瘤合并最多的DIC(弥散性血管内凝血)的诊断标准、治疗方法,诸如试用肝素、ATⅢ制剂、蛋白分解酶抑制剂等,以及早期发现和治疗效果的评价等,不断有所报道。伴随人口的高龄化,伴有其他疾病的病例很多,这些疾病及其治疗,往往加剧恶性肿瘤所带来的凝血异常。为了提高恶性肿瘤治疗效果,必须充分注意这个问题。本稿以恶性肿瘤与凝血系统的关系为中心,进行论述。
As we all know, there are various relationships between malignant tumors and coagulation disorders. Research on its causes has gradually progressed. Blood platelets and vascular endothelial cells involved in blood coagulation and fibrinolytic system have an important relationship with the proliferation and metastasis of malignant cells, and in particular, diagnostic standards and treatment methods for malignant intracancer DIC (disseminated intravascular coagulation), such as Trial heparin, ATIII preparations, proteolytic enzyme inhibitors, etc., as well as the evaluation of early detection and treatment effects, have been reported. As the population ages, there are many cases accompanied by other diseases. These diseases and their treatments often exacerbate coagulation abnormalities caused by malignant tumors. In order to improve the treatment of malignant tumors, we must pay full attention to this issue. This article focuses on the relationship between malignant tumors and the coagulation system.