血管内皮细胞和平滑肌细胞间存在着肌内皮缝隙连接,内皮细胞除通过释放血管活性物质影响下方平滑肌细胞的活动外,也可通过肌内皮缝隙连接调节平滑肌的功能,因此,肌内皮缝隙连接在血管功能调节中具有重要作用,并与病理状态下的血管功能异常有密切关系。 Vascular endothelial cells and smooth muscle cells exist in the gap junction of the muscle endothelial cells, endothelial cells in addition to the release of vasoactive substances affect the underlying smooth muscle cells in the activity, but also through the gap junction of the muscle endothelial regulating smooth muscle function, so the muscle endothelium gap connected to the blood vessels Function regulation plays an important role, and with the pathological state of vascular dysfunction are closely related.