肿瘤放疗和化疗过程中都存在较大的毒副作用,而肿瘤靶向性治疗既能降低毒副作用、减少用药量,又可提高药物的疗效。筛选与肿瘤特异性结合多肽已成为实现靶向治疗肿瘤的热点之一,并取得了一定的成果。肺癌目前的治疗方法主要是手术和放、化疗,虽然可以增加患者的存活率,但放、化疗毒副作用明显,耐受性差。现将与肺癌靶向性有关的多肽研究进展综述如下。 Tumor radiotherapy and chemotherapy in the process there are larger side effects, and tumor-targeted therapy can reduce the side effects, reduce the dosage, but also improve the efficacy of the drug. Screening and tumor-specific binding of peptides has become one of the hot spots to achieve targeted therapy of tumors, and achieved some results. The current treatment of lung cancer is mainly surgery and radiotherapy and chemotherapy, although it can increase the survival rate of patients, but radiotherapy and chemotherapy toxicity side effects, poor tolerance. The research progress of the peptides related to lung cancer targeting now are summarized as follows.