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一种用以克服柳氮磺胺吡啶(sulphasalaz-ine)在溃疡性结肠炎患者中产生副作用的新口服配方已由英国威尔士的医院药师设计出来,并在临床观察中得到了满意的效果。威尔士大学医院的研究者们报告说,该配方的5-氨基水杨酸(柳氮磺胺吡啶的有效成分),对那些不能服用柳氮磺胺吡啶的患者都能很好地耐受。柳氮磺胺吡啶广泛应用于溃疡性结肠炎的维持治疗,但是由于该药的不良反应和过敏性以致某些病人无法耐受
A new oral formulation to overcome the side effects of sulphasalazine in patients with ulcerative colitis has been designed by hospital pharmacists in Wales, United Kingdom and has been shown to be satisfactory in clinical observations. Researchers at the University Hospital of Wales reported that 5-aminosalicylate (the active ingredient of sulfasalazine) in this formulation is well tolerated in those who can not take sulfasalazine. Sulfasalazine is widely used in the maintenance treatment of ulcerative colitis, but due to adverse drug reactions and allergic to some patients can not tolerate