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离体人血红细胞受到低能的软X射线照射后,如同受到硬X射线照射一样,细胞表面电荷明显下降,这种变化可用细胞电泳率的下降来表示。剂量在43.9～1754.0rad范围内,红细胞电泳率的变化与剂量呈正比。受43.9和1052.4rad软X射线照射后,红细胞电泳率随时间的推移逐渐下降,照后4小时降到最低点,以后逐渐恢复,43.9rad照后24小时可以恢复到未受照射的对照水平,而1052.4rad照射组则不能。 红细胞悬浮于自身血浆中,其电泳率比悬浮于生理盐水中低。照射的血浆加到红细胞悬液中并不能改变红细胞的电泳率;而受照的红细胞悬浮于生理盐水中,却可降低其电泳率。加胞二磷胆碱到照后的红细胞悬液中,可使红细胞表面电荷得到恢复。
The isolated human red blood cells are exposed to low-energy soft X-rays, and as with hard X-rays, the surface charge of the cells is significantly reduced. This change can be represented by a decrease in the electrophoretic rate of cells. The doses ranged from 43.9 to 1754.0 rad. The electrophoretic rate of red blood cells was proportional to the dose. After electrophoresis at 43.9 and 1052.4 rad soft X-rays, the red blood cell electrophoresis rate gradually decreased with time, dropped to the lowest point 4 hours after exposure, and gradually recovered afterwards, and recovered to unirradiated control levels 24 hours after 43.9 rad irradiation. The 1052.4rad irradiation group cannot. Erythrocytes are suspended in their own plasma and their electrophoresis rate is lower than that in normal saline. Irradiated plasma added to the erythrocyte suspension does not change the electrophoretic rate of the erythrocytes. Irradiated erythrocytes suspended in physiological saline can reduce the electrophoresis rate. Adding Citicholine to the irradiated red cell suspension can restore the red cell surface charge.