本文报道用氮甲及氮甲为主联合化疗方案治疗36例多发性骨髓瘤。43程化疗的缓解率为49％,客观有效率68％,骨痛好转率达97％。1、3、5年生存率为89％、47％和33％。中位生存期35个月。副作用有胃肠反应和骨髓抑制。氮甲可作为治疗多发性骨髓瘤的首选药。 In this paper, we reported that 36 patients with multiple myeloma were treated with a combination of N2 and N2 combined chemotherapy. The remission rate of 43-way chemotherapy was 49%, the objective effective rate was 68%, and the improvement rate of bone pain was 97%. The 1-, 3-, and 5-year survival rates were 89%, 47%, and 33%. The median survival period is 35 months. Side effects include gastrointestinal reactions and myelosuppression. Nitrogen can be used as the first choice for the treatment of multiple myeloma.