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在突触的可塑性上,如海马的长时程增强(LTP)和小脑的长时程阻抑(LTD),NO具有扩散性信息递质的作用。 1991年有人发现,在海马的CA1区的LTP对建立场所记忆是重要的。通过实验研究,关于LTP的形成有二种学说,一种是把突触前进质释放的增加作为突触前学说,另一种是把突触后细胞的受体敏感性和数目增加作为突触后学说。但二者均无定论。关于LTP形成上NO的作用也存在二种对立的观点,一种认为,NO是与建立场所记忆有关的梅马CA1区的LTP形成
In terms of synaptic plasticity, such as long-term potentiation (LTP) in the hippocampus and long-term inhibitory (LTD) in the cerebellum, NO has the effect of diffusive information transmitter. It was found in 1991 that LTP in the CA1 area of the hippocampus is important for establishing site memory. Through experimental research, there are two theories about the formation of LTP. One is to increase the release of synaptic progenitor as a presynaptic theory and the other is to increase the receptor sensitivity and number of postsynaptic cells as a synapse After the doctrine. But both are inconclusive. There are also two opposing views about the role of NO on the formation of LTP. One is that NO is the formation of LTP in the meqal CA1 region associated with site memory