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肌腱蛋白Ｒ（ｔｅｎａｓｃｉｎＲ，ＴＮＲ）是一种重要的细胞外基质糖蛋白（ｅｘｔｒａｃｅｌｕｌａｒｍａｔｒｉｘ，ＥＣＭ）．分布于中枢神经系统，主要在髓鞘形成早期的少突胶质细胞中表达，成熟的胶质细胞及某些神经元（如脊髓，视网膜，小脑和海马的中间神经元）也有表达．ＴＮＲ具有复杂的结构，由三种不同的结构域组成，从氨基端到羧基端依次为：类似于表皮生长因子的重复片段，类似于Ⅲ型纤连蛋白重复片段，类似（血）纤维蛋白原片段组成．ＴＮＲ具有多种复杂的功能，对神经元具有排斥作用，促进或抑制神经元突起的生长，诱导神经元形态的极性化，并和髓鞘的形成有关，ＴＮＲ结构的复杂性和功能的多样性提示，ＴＮＲ有多个受体存在，已经发现的受体有Ｆ３／Ｆ１１，ＭＡＧ，ＸＬ１，Ｘｐｒｏｃａｎ等．
Tenascin R, TN R is an important extracellular matrix protein (extracelularmatrix, ECM). Distributed in the central nervous system, mainly in the early formation of myelin oligodendrocyte expression, mature glial cells and some neurons (such as the spinal cord, retina, cerebellar and hippocampal interneurons) are also expressed. TN R has a complex structure, composed of three different domains, from the amino end to the carboxy end followed by: similar to epidermal growth factor repeat fragments, similar to type Ⅲ fibronectin repeats, similar (blood) fiber Pro-protein fragments. TN R has a variety of complex functions, have a repulsive effect on neurons, promote or inhibit the growth of neuronal protrusions, induce the polarity of neuronal morphology, and the formation of myelin, TN R structure complexity And functional diversity tips, TNR has multiple receptors exist, have been found receptors F3 / F11, MAG, XL1, Xprocan and so on.