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分散片是目前国际上刚刚兴起的一种新的特殊剂型,已由《英国药典》1993年版载为法定剂型。分散片有以下几个特点:a.在20℃±1℃水中三分钟内崩散,崩散后的混悬液体能通过710μm筛孔。由于提高了药物的溶出速度和溶解度,故提高了生物利用度,实现了药物的速效高效。b.服用时可按片剂服用,也可置于牛奶、冰淇淋或饮料中服用,且口感良好,方便了儿童和行动不便的老人用药。c.分散片与颗粒、干混悬剂有很多相似之处,但制备工艺、生产效率、产品质量、设备要求、包装等均优于上述两种剂型。
Dispersing tablets is a new special dosage form that is just emerging in the world at present. It has been prescribed by the British Pharmacopoeia in 1993 edition. Dispersing tablets have the following characteristics: a. Disintegrated in water at 20 ℃ ± 1 ℃ within three minutes, after the collapse of the suspended liquid through the 710μm sieve. Due to the increased dissolution rate and solubility of the drug, the bioavailability is improved and the drug is rapidly and efficiently achieved. b. When taking tablets can be taken, can also be placed in milk, ice cream or drink to take, and good taste, convenient for children and the elderly with limited mobility medication. c. dispersible tablets and granules, dry suspension has many similarities, but the preparation process, production efficiency, product quality, equipment requirements, packaging, etc. are superior to the two formulations.