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对140例老年高血压类型、年龄、合并缺血性脑血管病的例数及血脂、载脂蛋白、血液流变学进行统计学处理,分析它们之间的关系。结果表明:随增龄,(Ⅰ型)收缩期型高血压的比例增多,(Ⅱ型)混合型高血压次之,(Ⅲ型)舒张期型高血压随增龄减少。缺血性脑血管病占高血压病的30%,脑梗塞居多,其中腔隙性脑梗塞占52.63%,脑出血占9%。缺血性脑血管病的高发年龄在65~75岁,以Ⅰ、Ⅱ型高血压为主。高血压组和脑血管病组的血脂、血粘滞度增高与对照组比较P<0.01。载脂蛋白APOA1/APOB比值下降。脑出血患者的载脂蛋白无明显变化。提示老年高血压是缺血性脑血管病重要危险因素之一,其类型、年龄、血脂、血液流变学及脑血管病之间关系密切。
140 cases of elderly type of hypertension, age, the number of cases of ischemic cerebrovascular disease and serum lipids, apolipoprotein, hemorheology were statistically analyzed and analyzed the relationship between them. The results showed that with the increase of age, the proportion of type Ⅰ systolic hypertension increased, while that of type Ⅱ hypertension followed by that of type Ⅲ diastolic hypertension decreased with age. Ischemic cerebrovascular disease accounts for 30% of hypertension, mostly cerebral infarction, lacunar infarction accounted for 52.63%, 9% of cerebral hemorrhage. The high incidence of ischemic cerebrovascular disease in the 65 to 75 years old, mainly Ⅰ, Ⅱ type of hypertension. Blood pressure and blood viscosity in hypertension group and cerebrovascular disease group were higher than those in control group (P <0.01). Apolipoprotein APOA1 / APOB ratio decreased. Apolipoproteins in patients with cerebral hemorrhage no significant change. It is suggested that senile hypertension is one of the important risk factors of ischemic cerebrovascular disease, and its type, age, blood lipid, hemorheology and cerebrovascular disease are closely related.