上皮型钙粘蛋白 (E Cadherin)是一种重要的细胞粘附分子和信号转导分子 ,参与组织形态发生、胚胎发育和细胞命运过程 ,其作为细胞粘附分子的功能是控制细胞移动。已发现E cadherin与肿瘤的发生发展有密切关系 ,并已有一些资料报道血清可溶性E Cadherin与恶性肿瘤的病情有一定关系 ,并试图探讨其作为一种新的诊断标志和治疗效果、预后判断的一个指标。本文就近几年有关E Cadherin与肿瘤的关系及其血清学检测进行综述。 Epicadherin (E Cadherin) is an important cell adhesion molecule and signal transduction molecule involved in tissue morphogenesis, embryonic development and cell fate processes. Its function as a cell adhesion molecule is to control cell migration. It has been found that E cadherin is closely related to the occurrence and development of tumors, and some data have reported that serum soluble E Cadherin has a certain relationship with the condition of malignant tumors, and attempts to explore it as a new diagnostic marker and therapeutic effect, prognosis judgment One indicator. This article reviews the relationship between E Cadherin and tumors and their serological tests in recent years.