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对1979年4月—1984年10月期间7,676例次胃粘膜活检材料中检出的362例轻度以上异型增生的病例进行了观察。到1985年3月止,有随访结果者100例(27.6%),随访时间0.5—5年,平均22个月,随访次数1—6次,平均1.8次/人。100例异型增生的随访结果如下:19例病变减轻,57例保持不变,24例病变加重,其中7例发生癌变,胃手术切除标本经病理证实均属早期胃癌,包括微小胃癌和小胃癌各1例。此外,对异型增生的演变趋势、临床处理原则及胃镜病理活检的意义作了讨论和评价。本研究提示,对胃粘膜异型增生病例进行定期随访,不失为当今胃癌计划防治工作的重要实际手段。
A total of 362 cases of mild dysplasia were detected in 7,676 cases of gastric biopsy materials from April 1979 to October 1984. As of March 1985, there were 100 cases (27.6%) of follow-up results, follow-up time 0.5-5 years, an average of 22 months, follow-up frequency of 1-6 times, an average of 1.8 times / person. The follow-up results of 100 cases of dysplasia were as follows: 19 cases of lesions were reduced, 57 cases remained unchanged, and 24 cases were aggravated. Among them, 7 cases were cancerous. Gastric surgical resection specimens were pathologically confirmed to be early gastric cancer, including small gastric cancer and small gastric cancer. 1 case. In addition, the development trend of dysplasia, clinical treatment principles and the significance of gastroscope biopsy were discussed and evaluated. This study suggests that regular follow-up of gastric dysplasia cases is an important practical tool for prevention and treatment of gastric cancer.