龋病是一种微生物感染性疾病,变形链球菌是引起其发生发展的主要致龋菌之一。近年来天然药物对龋病防治的研究已成为热点,而蜂胶是一种天然抗菌剂,国内外相关研究表明蜂胶对变形链球菌的生长、产酸、粘附、产胞外多糖及牙菌斑等方面有抑制的作用。本研究就蜂胶对变形链球菌的主要致龋毒力因子的作用研究作一综述。 Dental caries is a microbial infection disease, Streptococcus mutans is one of the major cariogenic bacteria that causes its development. In recent years, natural medicine has become a hot spot on the prevention and treatment of dental caries. Propolis is a natural antibacterial agent. Studies at home and abroad show that propolis can affect the growth, acid production, adhesion, extracellular polysaccharides and plaque of Streptococcus mutans Inhibition and other aspects of the role. In this study, the effects of propolis on the major cariogenic virulence factors of Streptococcus mutans were reviewed.