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目的:观察综合性疗法在功能性消化不良中的应用效果,为提高该类患者的治疗质量提供指导依据。方法:将浙江大学医学院附属第二医院2005年3月至2014年3月收治的62例功能性消化不良患者,按照治疗方法分成观察组与对照组,均31例,对照组采用常规消化系统药物进行治疗,观察组在常规疗法的基础上联合抗抑郁药物、心理干预等进行综合性治疗,比较两组患者的治疗效果。结果:观察组患者的治疗有效率显著高于对照组,差异有统计学意义(P<0.05);观察组治疗后的焦虑自评量表(SAS)、抑郁自评量表(SDS)、功能性消化不良症状评分均显著低于对照组患者,差异均有统计学意义(均P<0.05);两组的不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在使用常规消化系统药物的基础上联合抗抑郁治疗、心理干预等综合性疗法治疗功能性消化不良患者,可提高临床疗效,改善患者的不良情绪与临床症状,安全性高,具有广泛推广价值。
Objective: To observe the effect of comprehensive therapy in functional dyspepsia, and to provide guidance for improving the quality of treatment in these patients. Methods: Sixty-two patients with functional dyspepsia admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine from March 2005 to March 2014 were divided into observation group and control group according to the treatment method, all of which were in the control group. Conventional digestive system Drug treatment, the observation group in the conventional therapy based on antidepressants, psychological interventions and other comprehensive treatment, the treatment effect of two groups of patients were compared. Results: The treatment effective rate in the observation group was significantly higher than that in the control group (P <0.05). SAS, SDS, The score of sexual dyspepsia was significantly lower than that of the control group (all P <0.05). There was no significant difference in adverse reaction between the two groups (P> 0.05). Conclusion: The combination of antidepressant therapy and psychological intervention can improve the clinical curative effect, improve the patients’ bad mood and clinical symptoms, and have the advantages of extensive safety value.