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观察低分子量肝素(LMWH)对急性脑梗塞的疗效。方法:试用LMWH腹壁皮下注射治疗急性脑梗塞30例,以低分子右旋糖酐静脉滴注治疗24例作为对照。结果:LMWH组与对照组的显效率分别为66.7%与45.8%(P<0.05),总有效率分别为86.7%与66.7%(P<0.05),LMWH组功能恢复明显优于对照组(P<0.05)。LMWH组17例治疗后与治疗前作CT或MRI检查,显示脑梗塞灶体积明显缩小(P<0.01)。治疗中未出现自发性出血。结论:初步认为LMWH对急性脑梗塞有较肯定的疗效,且方法简便、易行、安全。
To observe the effect of low molecular weight heparin (LMWH) on acute cerebral infarction. Methods: 30 cases of acute cerebral infarction were treated with subcutaneous injection of LMWH abdominal wall, 24 cases were treated by low molecular weight dextran intravenous infusion. Results: The effective rates of LMWH group and control group were 66.7% and 45.8% respectively (P <0.05), and the total effective rates were 86.7% and 66.7% (P <0.05) , LMWH group function recovery was significantly better than the control group (P <0.05). 17 cases of LMWH group after treatment and before treatment for CT or MRI showed that infarct size was significantly reduced (P <0.01). Spontaneous bleeding did not occur during treatment. Conclusion: It is preliminarily believed that LMWH has definite curative effect on acute cerebral infarction, and the method is simple, easy and safe.