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目的为了解仙居县健康人群乙脑免疫水平及乙脑流行规律,为乙脑防控提供依据。方法随机抽取不同年龄、性别、地区的健康人群在流行前期、后期的双份静脉血,采用酶联免疫吸附(ELISA)法检测乙脑抗体(IgG)。结果 2005年-2012年共监测健康人群3741人,乙脑抗体阳性率42.79%;流行后期抗体阳性率50.32%,非常显著的高于流行前期36.32%;15岁以下和60岁以上各年龄组流行后期抗体阳性率非常显著的高于流行前期;不同性别、不同地区乙脑抗体阳性率差异无统计学意义。结论仙居县健康人群乙脑抗体水平偏低,需进一步做好乙脑疫苗接种工作,消除乙脑免疫空白,提高接种率和接种质量是防止和减少乙脑发病的有效措施。
Objective To understand the epidemic situation of Japanese encephalitis B and the epidemic trend of Japanese encephalitis among healthy population in Xianju County and provide basis for preventing and controlling JE. Methods Twice venous blood was randomly collected from healthy population of different age, gender and region before and after the epidemic. Encephalitis antibody (IgG) was detected by enzyme-linked immunosorbent assay (ELISA). Results A total of 3741 healthy people were monitored from 2005 to 2012, the positive rate of Japanese encephalitis B was 42.79%. The positive rate of antibody was 50.32% at the late epidemic stage, which was significantly higher than that of the prevalence 36.32% The positive rate of late antibody was significantly higher than that of the pre-epidemic period. There was no significant difference in the positive rate of Japanese encephalitis antibody between different sexes and different regions. Conclusions JE antibody levels in healthy people in Xianju County are low, so JE vaccine should be further vaccinated to eliminate JE immunization blank. Improving vaccination rate and vaccination quality is an effective measure to prevent and reduce the incidence of JE.