根据前人报道,疟疾鼠的免疫脾细胞经继承性转移后,受鼠就有抗伯氏鼠疟原虫感染的抵抗力。另外,环磷酰胺(Cyclophosphamide,下简称为CY)除了有其他作用之外,还有严重损坏疟疾大鼠形成免疫球蛋白的潜能。在小鼠,B细胞群对CY所致的损坏特别敏感。因此本文作者设想,CY处理大鼠后免疫球蛋白合成受到明显抑制的直接原因,乃是B细胞也有类似的损坏。按照这些设想,进行了本题实验。 According to previous reports, the malaria mice immunocompetent splenocytes after inherited metastasis, the mice have resistance against the infection of P. murine parasite. In addition, Cyclophosphamide (CY), in addition to its other effects, has the potential to severely damage the formation of immunoglobulins in malaria rats. In mice, the B cell population is particularly susceptible to CY-induced damage. Therefore, the authors assume that the direct reason for the significant inhibition of immunoglobulin synthesis after CY treatment in rats is that B cells also have similar damage. According to these ideas, carried out the test of this topic.