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目的探讨次声对船员某些生理生化功能的影响。方法两艘同类型船分为试验船(试验组)和对照船(对照组)。两船同时出航,同时返航,试验时同时关闭主机。试验船的次声装置连续工作6 h,船上主要舱室和工作位置的次声级为105.0~117.0 dB,其频谱能量12.5~20.0 Hz。对照船未启动次声装置,其它条件与试验船基本相同。试验前后采集两组船员血样,检测血清免疫指标3项,血浆和溶血液生化指标11项。结果经连续6 h次声环境暴露后,试验组船员血清IgG测得值为(13.99±1.73)g/L,比航前测得值(13.27±1.61)g/L增加(P<0.01),也较对照组航后测得值(13.75±2.94)g/L增加(P<0.05)。试验组船员血浆GSH(还原型谷胱甘肽)测定值为(272.08±39.10)mg/L,比航前测定值(231.18±25.39)mg/L增加17.69%(P<0.01),而对照组航后增加12.42%。航行作业后,试验组RBC-ChE和T-LDH分别比航前升高236.6%和122.6%,而对照组无大的变化,可能与次声环境有关。另外,两组红细胞Ca2+-ATPase和血清T-AOC也比航行作业前有明显下降(P<0.05和P<0.01)。其它指标的变化,大多在正常参考值范围。结论在本研究条件下,船员部分血液指标如RBC-ChE,T-LDH和GSH出现明显的变化,可能与次声作用有关。
Objective To investigate the effect of infrasound on some physiological and biochemical functions of seafarers. Methods Two ships of the same type were divided into test ship (experimental group) and control ship (control group). At the same time the two ships sailing, at the same time return home, while the test off the host. The infrasound of the test ship operated continuously for 6 h. The infrasound level of the main cabin and working position on the ship was 105.0-117.0 dB, and its spectral energy was 12.5-20.0 Hz. The control ship did not activate the infrasound device, and other conditions were basically the same as those of the test ship. Blood samples of two crew members were collected before and after the test, three indexes of serum immunity and 11 biochemical indexes of plasma and hemolysis were detected. Results Serum IgG of the test group was (13.99 ± 1.73) g / L after exposed to infrasound for 6 hours, which was significantly higher than that of pre-flight measurement (13.27 ± 1.61) g / L (P <0.01) Compared with the control group, the measured value (13.75 ± 2.94) g / L was also increased (P <0.05). The plasma GSH level in the test group was (272.08 ± 39.10) mg / L, an increase of 17.69% (231.01 ± 25.39) mg / L compared with that in the control group After the flight increased by 12.42%. After sailing, the RBC-ChE and T-LDH in the experimental group increased by 236.6% and 122.6% respectively compared with the pre-flight, but no significant change in the control group, which may be related to infrasound. In addition, Ca2 + -ATPase and T-AOC in serum of two groups were significantly lower than those before sailing (P <0.05 and P <0.01). Other indicators of changes, mostly in the normal reference range. Conclusion Under the conditions of this study, some blood parameters such as RBC-ChE, T-LDH and GSH of the crew changed significantly, which may be related to infrasound.