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目的:探讨肾结石并发肾盂鳞状细胞癌的临床特征并总结避免漏诊误诊的经验。方法:对4例肾结石合并肾盂鳞状细胞癌患者的临床资料进行了回顾性分析,并复习相关文献。4例患者均因肾结石行经皮肾镜取石术(PCNL),术前检查均未发现肾脏有明显肿瘤性病变,术中均发现黏膜异常,但均未发现明显向腔内突出的肿瘤样病变。术中取活检,术后均报告为鳞状细胞癌。4例患者随后均行根治性肾切除术。结果:2例术后至今生存,2例分别于术后6个月、10个月死亡。结论:通过此次回顾及文献复习,我们认为肾结石应及时治疗,对于长期患有肾结石的患者,应警惕合并肾脏肿瘤的可能性,并强调在治疗长期存在的肾结石的过程中,应注重对肾盂肾盏的组织活检。
Objective: To investigate the clinical features of renal calculi associated with renal pelvic squamous cell carcinoma and to summarize the experience of avoiding misdiagnosis. Methods: The clinical data of 4 patients with nephrolithiasis and renal squamous cell carcinoma were analyzed retrospectively, and the related literatures were reviewed. All 4 patients underwent percutaneous nephrolithotomy (PCNL) due to renal calculi. No significant neoplastic lesions were found in the kidneys during the preoperative examination. The mucosal abnormalities were found in the operation, but no obvious tumor-like lesions were found in the cavity . Surgical biopsy, were reported after squamous cell carcinoma. All 4 patients underwent radical nephrectomy. Results: Two patients survived till now and two died at 6 months and 10 months respectively. CONCLUSIONS: Through this review and review of the literature, we believe that kidney stones should be treated promptly, and patients with long-term kidney stones should be alerted to the possibility of renal cancer and to emphasize the importance of treating kidney stones in the long term Biopsy of the renal pelvis calyx.