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目的 缺血性肝炎是缺血缺氧导致的可逆性肝损害。通过对 49例缺血性肝炎临床表现、实验室检查和预后进行分析 ,探讨其临床特点。方法 对患者的临床表现、血清丙氨酸转氨酶 (ALT)、天门冬氨酸转氨酸 (AST)、乳酸脱氢酶 (LDH)及其他生化指标和动脉血氧分压进行监测 ,直到恢复正常或患者死亡。结果 缺血性肝炎主要发生在心力衰竭、呼吸衰竭和急性低血压疾病基础上 ;临床表现主要为低血压和缺氧 ;ALT、AST和LDH均极度增高 ,并随病情好转而迅速恢复 ;死亡率达 46 9% ,均死于原有基础疾病 ,其中AST/ALT大于或等于 1者显著高于小于1者。结论 缺血性肝炎是心力衰竭、呼吸衰竭和急性低血压时的一种并发症 ,ALT、AST和LDH的可逆性极度增高是缺血性肝炎的主要特点
The purpose of ischemic hepatitis is reversible liver damage caused by hypoxia and hypoxia. Through the clinical manifestations of 49 cases of ischemic hepatitis, laboratory tests and prognosis were analyzed to explore the clinical features. Methods The clinical manifestations, serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and other biochemical parameters and arterial oxygen pressure were monitored until normal Or the patient dies. Results Ischemic hepatitis mainly occurred on the basis of heart failure, respiratory failure and acute hypotension. The main clinical manifestations were hypotension and hypoxia. ALT, AST and LDH were extremely increased and recovered rapidly with the improvement of the disease. Up to 46.9%, all died from the original underlying diseases, AST / ALT greater than or equal to 1 were significantly higher than less than one. Conclusions Ischemic hepatitis is a complication of heart failure, respiratory failure and acute hypotension. The extremely high reversibility of ALT, AST and LDH is the main characteristic of ischemic hepatitis