本文测定了一些抗癌药物对部分纯化的小牛胸腺DNA聚合酶α和末端脱氧核苷酰转移酶活性的抑制作用。这两个酶同时经过了35～50％硫酸铵沉淀和磷酸纤维素柱层析。本文对一些治疗白血病的常用药物,如环磷酰胺,氨甲喋呤,长春新碱,阿糖胞苷等;中草药(补中益阴汤),及其中的六味草药单方分别测定了对这两个酶活性的抑制作用,并进行了比较。可以看出,环磷酰 This article determined the inhibitory effect of some anticancer drugs on partially purified calf thymus DNA polymerase alpha and terminal deoxynucleotidyl transferase activity. The two enzymes are simultaneously subjected to 35-50% ammonium sulfate precipitation and phosphocellulose column chromatography. In this paper, some of the commonly used drugs for the treatment of leukemia, such as cyclophosphamide, methotrexate, vincristine, cytarabine, etc .; Chinese herbal medicine (Buzhongyi Yin Tang), and six herbs were unilaterally determined the activity of these two enzymes The inhibitory effects were compared and compared. It can be seen that cyclophosphoryl