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唾液酸是存在于细胞膜上的一个成份。癌细胞表面的唾液酸含量高于相应的正常细胞。癌瘤的抗元性、扩散与转移都与癌细胞表面的唾液酸有密切的关系。 Kafka,V.等在1977年报道唾液酸是血清糖蛋白变化的一个敏感指标,可应用于人癌瘤生长的动态追踪。其它作者也有报道认为某些癌患者血清中唾液酸含量可高于正常人,而且含量的升高与降低又同癌瘤的消退,复发,转移有一定的关系。
Sialic acid is a component that is present on the cell membrane. The sialic acid content on the surface of cancer cells is higher than that of the corresponding normal cells. Cancer resistance, proliferation and metastasis are closely related to the sialic acid on the surface of cancer cells. Kafka, V., et al., reported in 1977 that sialic acid is a sensitive indicator of changes in serum glycoproteins and can be applied to the dynamic tracking of human cancer growth. Other authors have also reported that the serum sialic acid content in some patients with cancer may be higher than normal, and the increase and decrease in the content of cancer patients have a certain relationship with the regression, recurrence and metastasis of cancer.