论文部分内容阅读
早些时候,本人对肿瘤的发生机理提出了一个假说,即幼稚细胞分化受阻假说。该假说的主要思想如下。 1.肿瘤只发生在未分化成熟、且尚具有分裂能力的细胞。肿瘤不会发生在已分化成熟或虽未完全分化成熟但已无分裂能力的细胞。即肿瘤只发生于有分裂能力的幼稚细胞。 2.无论何种原因引起的任何肿瘤,其共同的发生机制为幼稚细胞分化受阻。 3.肿瘤细胞不是“异己细胞”,除了不能分化成熟,它可以是完全正常的细胞,与同一分化阶段的同一种正常细胞没有两样。用幼稚细胞分化受阻假说,可以解释与
Earlier, I proposed a hypothesis about the mechanism of tumorigenesis, that is, the hypothesis that the differentiation of immature cells is blocked. The main idea of this hypothesis is as follows. 1. Tumors only occur in undifferentiated and mature cells that still have the ability to divide. Tumors do not occur in cells that have matured or are not fully differentiated but have no ability to divide. That is, tumors only occur in immature cells that have the ability to divide. 2. Regardless of the cause of any tumor, its common mechanism is that the differentiation of immature cells is blocked. 3. Tumor cells are not “isolated cells.” Except that they are unable to differentiate and mature, they may be completely normal cells, and they do not differ from the same normal cells in the same differentiation stage. The hypothesis of impaired differentiation of immature cells can explain