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目的:了解重庆市渝北区育龄妇女孕前弓形虫(TOX)、风疹病毒(RV)及巨细胞病毒(CMV)3项病毒感染状况,为优生优育工作提供依据。方法:收集2010年的1 998份育龄妇女血清标本,用ELISA法进行TOX、RV和CMV抗体检测,用SPSS11.5统计软件对资料进行分析。结果:TOX累计及新发感染率分别为2.0%和1.0%,各年龄组间TOX累计及新发感染率差异均有统计学意义(P<0.05);RV-IgG抗体阳性率为13.3%,不同年龄组育龄妇女RV抗体阳性率差异有统计学意义(P<0.05),20～30岁人群相对易感;CMV累计及新发感染率分别为14.0%和0.6%,不同年龄组育龄妇女CMV累计感染率差异有统计学意义(P<0.05),但CMV新发感染率差异无统计学意义(P>0.05)。结论:重庆市渝北区育龄妇女TORCH3项病毒感染率偏低,人群普遍易感,应积极加强对育龄妇女人群孕前TORCH检查,以达到优生目的。
Objective: To understand the prevalence of TOX, RV and CMV in women of childbearing age in Yubei District of Chongqing City, and to provide basis for prenatal and postnatal care. Methods: A total of 1 998 women of childbearing age in 2010 were collected for the detection of TOX, RV and CMV antibodies by ELISA. The data were analyzed by SPSS11.5 statistical software. Results: The TOX cumulative and new infection rates were 2.0% and 1.0%, respectively. There was a significant difference in TOX cumulative and new infection rates among all age groups (P <0.05). The positive rate of RV-IgG was 13.3% The positive rates of RV antibodies in different age groups of women of childbearing age were significantly different (P <0.05), and the age groups of 20 ~ 30 were relatively susceptible. The cumulative CMV and new infection rates were 14.0% and 0.6% respectively. The CMV The cumulative infection rate was statistically significant (P <0.05), but the difference was not statistically significant (P> 0.05). CONCLUSION: The prevalence of TORCH3 infection in Y-Bei district women in Chongqing is low and the population is generally susceptible. TORCH should be actively checked before pregnancy in women of child-bearing age so as to attain the goal of eugenics.