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目的 :探讨肺外恶性肿瘤患者肺内孤立性病灶 (EPM- SPN)定性诊断的可能性 ,评价 CT对此类病变鉴别诊断的价值。方法 :收集经证实的 EPM- SPN病例 10 3例 ,通过对年龄、性别、吸烟史、肺内外病灶的平均时间间隔、肺内结节或肿块的 CT形态学特征等多因素分析 ,探讨 EPM- SPN定性诊断的相关因素。 结果 :10 3例病例中原发性支气管肺癌、孤立性转移瘤、良性病灶分别为 4 8、4 8和 7例 ,平均年龄为 (5 7.6 9± 15 .77)岁 ,男女之比为 1.78∶ 1。原发性支气管肺癌和孤立性转移瘤组的平均年龄和男女比分别为 (6 3.5 0± 11.91)岁、1.88∶ 1和 (5 3.4 8± 16 .88)岁、1.89∶ 1;原发性肺癌组的平均发病年龄显著大于孤立性转移瘤组 (t=3.34,P=0 .0 2 )。各组吸烟率无显著性差异。原发性支气管肺癌和孤立性转移瘤组的两瘤平均时间间隔分别为(6 6 .78± 75 .2 )个月和 (2 8.4 0± 37.0 )个月 ,后者显著短于前者 (P<0 .0 5 ) ;时间间隔≥ 2 4个月 ,原发性肺癌例数明显增多(P<0 .0 5 )。原发性肺癌和孤立性转移瘤两组间“毛刺”和“光整”的显示率有显著性差异 (P<0 .0 1,P<0 .0 0 1) ;而“分叶”和“清楚边界”显示率无显著性差异。原发性肺癌组和孤立性转移瘤组肺部病灶的最大径有显著性差异 (P<0 .0 5 )。在病灶最?
Objective: To explore the possibility of qualitative diagnosis of solitary pulmonary lesions (EPM-SPN) in patients with extrapulmonary malignancies and to evaluate the value of CT in the differential diagnosis of such lesions. Methods: A total of 103 confirmed cases of EPM-SPN were collected and analyzed by multivariate analysis of age, sex, smoking history, mean time between internal and external lesions, CT morphological characteristics of pulmonary nodules or masses, SPN qualitative diagnosis of the relevant factors. Results: Of 103 cases, 48, 48 and 7 cases of primary bronchogenic carcinoma, solitary metastasis and benign lesion were found respectively. The average age was (7.66 ± 15.77) years old and the ratio of male to female was 1.78 : 1. The mean age and male to female ratio in patients with primary bronchogenic carcinoma and solitary metastasis were (6 3.5 ± 11.91) years, 1.88: 1 and (5 3.4 8 ± 16.88) years, respectively, 1.89: 1; The mean age at onset of lung cancer was significantly greater than that of solitary metastasis (t = 3.34, P = .0 2). No significant differences in smoking rates among groups. The average time interval between the two tumors in primary bronchogenic carcinoma and solitary metastatic tumor was (66.78 ± 75.2) months and (8.420 ± 37.0) months respectively, which was significantly shorter than the former (P <0. 05). At intervals of ≥ 24 months, the number of cases of primary lung cancer was significantly increased (P <0.05). There were significant differences between the two groups in primary lung cancer and solitary metastasis (P <0.01, P <0.01), while “lobulation” and There was no significant difference in the display rate of “clear border”. The maximum diameters of lung lesions in primary lung cancer group and solitary metastasis group were significantly different (P <0.05). In the lesions most?