在动脉粥样硬化过程中,脂质浸入主动脉内膜形成脂斑,是早期病变的显著形态学特征。脂质的浸入与血液和主动脉壁之间的细胞屏障——内皮的改变直接相关。脂斑的形成是在内膜的细胞成分直接参与下进行的。对动脉粥样硬化的形态学过程虽已有很多的研究,但关于参加脂质吞噬和脂斑形成的细胞成分的性质,仍没有一致的意见。 In the process of atherosclerosis, lipid into the aortic intima formation of the plaque, is a significant morphological features of early lesions. Lipid penetration is directly related to changes in the cell barrier between the blood and the aorta-endothelium. The formation of the plaque is carried out with the direct involvement of cellular components of the intima. Although there have been many studies on the morphological process of atherosclerosis, there is still no consensus on the nature of the cellular constituents involved in lipid phagocytosis and plaque formation.