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目的分析肺癌患者化疗期间发生感染的相关危险因素,为临床化疗治疗肺癌提供指导,降低感染率。方法回顾分析本院收治的350例行化疗的肺癌患者病历资料,分析相关因素与感染发生率之间的关系。结果患者的性别与是否合并肺部疾病和感染率比较,P>0.05,差异无统计学意义。患者的年龄、化疗的强度、肺癌的病理类型、临床分期、是否应用抗菌药物和免疫抑制剂、解剖学部位等因素与感染率比较,P<0.05,差异有统计学意义。结论肺癌患者化疗期间发生感染的相关危险因素中,除年龄不可控制外,其他的各个因素都与医疗过程有关。对肺癌化疗患者应提高预防感染发生的警惕性,在化疗期间合理决策医疗行为。
Objective To analyze the risk factors associated with infection during chemotherapy in patients with lung cancer and provide guidance for clinical chemotherapy in the treatment of lung cancer and reduce the infection rate. Methods The clinical data of 350 patients with lung cancer undergoing chemotherapy in our hospital were retrospectively analyzed, and the relationship between the related factors and the incidence of infection was analyzed. Results There was no significant difference between the sexes of patients and those with or without pulmonary diseases and infection rates (P> 0.05). The age of patients, the intensity of chemotherapy, the pathological types of lung cancer, clinical stage, whether the use of antimicrobial agents and immunosuppressive agents, anatomical sites and other factors compared with the infection rate, P <0.05, the difference was statistically significant. Conclusion Among the risk factors of infection in patients with lung cancer during chemotherapy, all the other factors are related to the medical process, except for the age can not be controlled. Chemotherapy in patients with lung cancer should raise awareness of the prevention of infection, reasonable decision-making during the chemotherapy of medical behavior.