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肺癌细胞学类型与病因有密切的关系,分析细胞学类型的变动趋势,有助于病因学的探讨。本文对广州市1980~1989年间死于肺癌的1093例肺癌患者的细胞学类型的变动趋势进行了分析。结果表明:男性有腺癌比例上升,鳞癌下降的趋势。女性则相反,表现为鳞癌上升腺癌下降。男女肺癌死者中吸烟者的比例在整个研究过程均没有明显变化,表明肺癌细胞学类型的变动可能是由吸烟以外的其他因素所引起。女性接触环境化学致癌物机会增多,可能是女性鳞癌比例上升、腺癌下降的原因。男性腺癌比例上升的原因,有待于进一步探讨。
There is a close relationship between the type of lung cancer cytology and its etiology. Analyzing the changing trends of cytology types is helpful to the etiology. This article analyzes the changes in the cytology types of 1093 lung cancer patients who died of lung cancer from 1980 to 1989 in Guangzhou. The results showed that: men have an increase in the proportion of adenocarcinoma and the tendency of squamous cell carcinoma to decline. In contrast, women showed a decrease in squamous cell carcinoma and adenocarcinoma. The proportion of smokers among male and female lung cancer deaths did not change significantly during the entire study period, suggesting that changes in lung cancer cytology may be caused by factors other than smoking. Increased opportunities for women to be exposed to environmental chemical carcinogens may be the reason for the increase in the proportion of women with squamous cell carcinoma and the decline in adenocarcinoma. The reason for the increase in the proportion of male adenocarcinomas remains to be further explored.