论文部分内容阅读
目的:探讨宫颈薄层液基细胞学检查(TCT)在宫颈上皮内瘤样病变(CIN)及早期癌筛查中的应用价值。方法:对2007年6月～2008年6月嘉兴市妇幼保健院门诊已婚妇女进行TCT(12 072例)和传统巴氏涂片(15 642例)检查,对细胞学检查结果异常(包括ASC-H以上病变)者,部分取活体组织检查(活检),送检病理诊断。结果:15 642例传统巴氏涂片样本中,阳性96例,阳性率为0.61%。经活检组织病理学诊断46例,阳性符合率为86.96%(40/46)。12 072例TCT受检样本中,阳性374例,阳性率为3.10%。经活检组织病理学诊断190例,阳性符合率为93.68%(178/190)。TCT阳性检出率明显高于传统巴氏涂片检出率,差异具有统计学意义(χ2=126.12,P<0.01)。结论:宫颈TCT可提高妇女CIN及早期癌的检出率,弥补传统巴氏涂片诊断的不足,提高了细胞学诊断的准确性。
Objective: To investigate the value of cervical cytology-based cytology (TCT) in cervical intraepithelial neoplasia (CIN) and early cancer screening. Methods: From June 2007 to June 2008, married women in outpatient clinic of Jiaxing MCH hospital were examined by TCT (12 072 cases) and traditional Pap smear (15 642 cases). The results of abnormal cytological examination (including ASC -H above lesions), some take living tissue examination (biopsy), sentinel diagnosis. Results: Of the 6464 cases of traditional Pap smears, 96 were positive, with a positive rate of 0.61%. 46 cases were diagnosed by biopsy histopathology, the positive coincidence rate was 86.96% (40/46). Among 12 072 TCT samples, 374 were positive, the positive rate was 3.10%. The biopsy histopathological diagnosis of 190 cases, the positive coincidence rate of 93.68% (178/190). The positive detection rate of TCT was significantly higher than that of the traditional Pap smear, the difference was statistically significant (χ2 = 126.12, P <0.01). Conclusion: Cervical TCT can improve the detection rate of CIN and early cancer in women, make up for the deficiency of traditional Pap smear diagnosis and improve the accuracy of cytological diagnosis.