单纯疱疹病毒(HSV)脑炎,是散发性脑炎中最常见的一种,约占散发性脑炎之20-75%,本病是一个严重而致死性疾病,死亡率60-80%,近年来发病有增高的趋势,引起国内外学者广泛的重视,自六十年代开始临床试用多种抗病毒药物以来,纵然众说纷云,毕竟死亡率有所降低,现将本病抗病毒化学疗法之近况综述如次:(一)疱疹净(碘苷Iododeoxyuridine、IDUR.IOU)IDU是胸腺核苷类似物,通过竞争并混入DNA占据胸腺核苷位置形成欺诈性DNA Herpes simplex virus (HSV) encephalitis is the most common type of sporadic encephalitis, accounting for 20-75% of sporadic encephalitis, the disease is a serious and fatal disease, the mortality rate of 60-80% In recent years, the incidence of increased trend, aroused widespread attention of scholars at home and abroad, since the 1960s began clinical trial of a wide range of antiviral drugs, even if the public are numerous, after all, reduce the mortality rate, now the disease antiviral chemotherapy The review is summarized as follows: (I) Iododeoxyuridine (IDUR.IOU) IDU is a thymidine analog that competes with DNA and occupies the thymidine position to form fraudulent DNA