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目的比较连续性血液净化(CBP)与普通血液透析(IHD)治疗老年急性肾功能衰竭(ARF)的疗效、预后及并发症。方法选取在某院就诊的老年急性肾衰患者38例,随机分为普通血液透析对照组和连续性血液净化治疗组,每组19例。对两组患者透析等综合治疗7 d、14 d、30 d的血清肌酐和尿素氮的水平,两组患者透析并发症情况、病死率情况等进行统计分析。结果两组并发症无明显的特异性及差异性,两组治疗方式对患者死亡率影响不具有统计学意义,CBP组,在治疗后7 d、14 d、30 d时,血清肌酐水平和尿素氮水平都低于IDH组,肾功能恢复较IDH组明显快。结论老年急性重症肾衰竭患者,应尽可能予以连续性血液净化治疗,促进肾功能恢复。
Objective To compare the efficacy, prognosis and complications of the treatment of senile acute renal failure (ARF) with continuous blood purification (CBP) and general hemodialysis (IHD). Methods Thirty-eight elderly patients with acute renal failure treated in a hospital were randomly divided into two groups: general hemodialysis group and continuous blood purification group, with 19 cases in each group. The levels of serum creatinine and urea nitrogen on the 7th, 14th and 30th day after dialysis were compared between the two groups. The complication and mortality of the two groups were analyzed statistically. Results There was no significant difference in the complication between the two groups. There was no significant difference between the two groups in the treatment mortality. In the CBP group, serum creatinine level and serum creatinine level were significantly increased at 7 d, 14 d and 30 d after treatment Nitrogen levels were lower than IDH group, renal function recovery was significantly faster than IDH group. Conclusion Aged patients with acute renal failure should be treated with continuous blood purification as far as possible to promote renal function recovery.