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目的分析科学合理的梅毒血清学检测和传染性诊断的方法,为有效防止梅毒经口岸传入传出提供依据。方法根据梅毒血清学检测方法的适用性和临床意义,确定出入境人员梅毒血清学检测方法;参考实验室血清学检测结果、患者的梅毒流行病学资料,确定梅毒传染性的诊断标准。结果出入境人员梅毒血清学检测可以采用TRUST和TPPA试验同时检测来进行梅毒血清学筛选,用TP-ELISA试验进行梅毒抗体确认。有条件的实验室可以采用PCR方法检测TP-DNA。结论出入境人员梅毒血清学检测及传染性诊断,必须结合病史、治疗史进行综合分析,判断梅毒是否具有传染性,决定是否签发健康检查证明书。
Objective To analyze the scientific and reasonable methods of serological and infectious diagnosis of syphilis and to provide a basis for effective prevention of syphilis from passing through the port. Methods According to the applicability and clinical significance of syphilis serological test, the method of serological detection of syphilis among immigrants was determined. According to the laboratory serological test results and the epidemiological data of syphilis patients, the diagnostic criteria of syphilis infectivity were determined. RESULTS: The syphilis serological test for entry-exit personnel can be carried out by syphilis serological screening using TRUST and TPPA tests, and the syphilis antibody was confirmed by TP-ELISA test. Qualified laboratories can detect TP-DNA by PCR. Conclusions The serological and infectious diagnosis of syphilis between entry and exit personnel must be combined with history and treatment history to make a comprehensive analysis to determine whether syphilis is contagious and decide whether to issue a certificate of health examination.