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目的：了解腹腔内化疗在晚期贲门癌中的临床作用。方法：对26例未能手术切除的晚期贲门癌患者，通过腹腔内置管或腹腔穿刺，用5－氟脲嘧啶500mg／m2和丝裂霉素5mg／m2行腹腔内化疗共189次。结果：部分缓解2例，好转10例；临床症状好转者占80．8％。中位生存期为8．7个月。结论：结合腹腔内化疗的原理和其影响因素，认为腹腔内化疗的毒副作用小，缓解晚期贲门癌患者的病情，改善其生活质量，但未能明显提高生存期。
Objective: To understand the clinical role of intraperitoneal chemotherapy in advanced cardiac cancer. METHODS: Twenty-six patients with advanced cardiac cancer who had not been surgically resected were treated with intraperitoneal or intraperitoneal puncture. A total of 189 intraperitoneal chemotherapy were performed with 5-fluorouracil 500 mg/m 2 and mitomycin 5 mg/m 2 . Results: Partial remission in 2 cases, improvement in 10 cases; clinical symptoms improved accounted for 80.8%. The median survival period was 8.7 months. Conclusion: According to the principle of intraperitoneal chemotherapy and its influencing factors, it is believed that the side effects of intraperitoneal chemotherapy are small, relieve the condition of patients with advanced cardial cancer, and improve their quality of life, but they can not significantly improve the survival period.