目的　探讨腔内钬激光治疗复杂输尿管结石的安全性和有效性。方法　总结输尿管镜下钬激光治疗 15 0例输尿管结石的临床资料 ,其中包裹合并息肉 15例 ,并有输尿管狭窄 2例。结果　输尿管上、中下段结石排净率分别为 85 .7%、96.8% ,并发症为 10 %。结论　钬激光结合腔内泌尿外科技术是治疗复杂输尿管结石首选的、安全有效的方法。 Objective To investigate the safety and efficacy of endoscopic holmium laser in the treatment of complex ureteral calculi. Methods The clinical data of 150 cases of ureteral calculi treated by ureteroscopic holmium laser were summarized. Among them, 15 cases were complicated with polyps and 2 cases had ureteral stricture. Results Ureter, middle and lower stones were 85.7%, 96.8%, complications were 10%. Conclusion Holmium laser combined with endourology is the first choice, safe and effective method for the treatment of complicated ureteral calculi.