单独给大鼠(n=5)氯化汞(10.9mg/kg/d×3)投药3天内全部死亡。但预先投以钼酸钠(300mg/kg/d×3)后再给同剂量氯化汞的动物全部存活。后者脑、肾、肝脏中汞含量比单独给氯化汞的动物减少,而肾、肝中钼含量增高,尿汞、尿钼日均排出量增高。脑中钼含量不增高。此现象提示钼有拮抗汞毒性作用。 All rats were killed (n = 5) mercuric chloride alone (10.9 mg / kg / d x 3) within 3 days of dosing. However, pre-cast sodium molybdate (300mg / kg / d × 3) and then give the same dose of mercuric chloride animals all survived. In the latter, the content of mercury in the brain, kidney and liver was decreased compared with that of mercuric chloride alone, while the content of molybdenum in kidney and liver was increased, and the average daily urinary mercury and urinary molybdenum excretion was increased. Molybdenum content in the brain is not increased. This phenomenon suggests that molybdenum has an antagonistic effect on mercury toxicity.