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可乐定(Clonidnum)又称氯压定或110降压药,属咪唑啉类降压药,化学名为二氯苄胺咪唑啉。自1962年合成后,发现它是一种具有镇静、减慢心率和降低血压的中枢性降压药。我国自70年代试用以来,现已广泛应用于临床。本文就近年来有关可乐定的临床药理研究进展作一叙述。药理作用及特点 1.作用原理:可乐定降压作用快而强,对各种体位均有降压作用。该药可选择性激活中枢孤束核
Clonidine (Clonidnum), also known as clonidine or 110 antihypertensive drugs, is an imidazoline antihypertensive drugs, chemical name dichlorobenzidine imidazoline. Since its synthesis in 1962, it has been found to be a central antihypertensive agent that is calming, slowing heart rate and lowering blood pressure. Since the 1970s, our country has been widely used in clinical trials. This article describes the progress in the clinical pharmacology of clonidine in recent years. Pharmacological effects and features 1. Therapeutic principle: Clonidine rapid and strong antihypertensive effect on all positions have antihypertensive effect. The drug can selectively activate the central nucleus tractus solitarius