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多种原因引起的眼睑退缩、眼睑缺损、眶周组织缺损、义眼台暴露等均需要合适的组织替代物植入到相应部位,而临床上常用的自体、异体及人工合成组织存在着操作方法复杂、炎症和排斥反应明显、组织相容性差等缺陷。以胶原为主要成分的脱细胞组织作为组织替代物可有效地避免上述并发症的出现,植入眼部进行睑板替代、眶周修复后能够介导宿主血管及成纤维细胞的长入,并维持正常的构型,而且植入局部的炎症及排斥反应轻微,是较理想的生物工程材料。
Eyelid retraction, eyelid defect, periorbital tissue defect, prosthetic eye exposure caused by a variety of reasons require proper replacement of the tissue into the corresponding site, and there are methods of operation in autologous, allogeneic and synthetic tissues commonly used clinically Complex, obvious inflammatory and rejection reactions, poor tissue compatibility and other defects. Collagen as the main component of acellular tissue as a tissue substitute can effectively avoid the above complications, implanted tarsal plate replacement, periorbital repair can mediate the growth of host blood vessels and fibroblasts, and Maintain the normal configuration, and implanted in the local inflammation and rejection is minor, is the ideal bio-engineering materials.