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本实验旨在研究传统处方“八味地黄”对心血管系统的药理作用。结果证明,八味地黄口服液可明显延长小鼠常压耐铁缺氧存活时间;明显保护垂体后叶素所致急性心肌缺血;显著降低氯仿所致小鼠室颤发生率;明显延长乌头碱所致心律失常出现的时间;明显抑制大鼠血小板聚集功能。为临床应用八味地黄口服液防治心血管疾病提供了药理实验依据。
This experiment aims to study the pharmacological effects of the traditional prescription “Bawei Dihuang” on the cardiovascular system. The results showed that Bawei Dihuang Oral Liquid can significantly prolong the survival time of iron and hypoxia in mice at atmospheric pressure; it can obviously protect acute myocardial ischemia induced by pituitrin; significantly reduce the incidence of ventricular fibrillation in mice induced by chloroform; The time of occurrence of arrhythmia caused by cephalosine; markedly inhibits platelet aggregation in rats. It provides pharmacological experimental basis for the clinical application of Bawei Dihuang Oral Liquid in the prevention and treatment of cardiovascular diseases.