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目的 :用 5 2 Fe-枸橼酸铁 PET显像测定肝豆状核变性(Wilson病 )病人脑组织的铁代谢改变。方法 :共检查肝豆状核变性病人 6例 (年龄 2 3～ 5 1岁 )和 16例健康志愿者。 PET检查前要求停用配位体数天 (1例未停用 )。在 3m in内用注射泵从静脉注入 5 2 Fe-枸橼酸铁 ,用PET显像仪
OBJECTIVE: To determine the changes of iron metabolism in brain tissue of patients with hepatolenticular degeneration (Wilson’s disease) by Fe 2 Fe-citrate PET imaging. Methods: A total of 6 hepatolenticular degeneration patients (aged 23-51 years) and 16 healthy volunteers were examined. Discontinuation of ligands for several days prior to PET examination (1 non-disabled). In 3 m in with a syringe pump from the vein 5 2 Fe-iron citrate, with a PET imager