消化性溃疡（ＰＵ）的发病因素很多，其中尤以高胃酸和幽门螺杆菌（Ｈｐ）感染最为重要，临床实践表明应用抗菌剂消除Ｈｐ后可促进溃疡愈合及防止溃疡复发［１～３］。目前国内在消除Ｈｐ时多选择羟氨苄青霉素、胶体铋、四环素、甲硝唑、克拉霉素、甲基红霉素等当中的３种... The incidence of peptic ulcer (PU) many factors, especially high stomach acid and Helicobacter pylori (Hp) infection is the most important clinical practice shows that the use of antimicrobial agents to eliminate Hp can promote ulcer healing and prevent ulcer recurrence [1-3]. Currently in the elimination of Hp when the choice of amoxicillin, colloidal bismuth, tetracycline, metronidazole, clarithromycin, methyl erythromycin and other three kinds of ...