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目的探讨后循环脑梗死与基底动脉弯曲的关系,分析影响后循环脑梗死的相关危险因素。方法回顾性分析314例脑梗死患者,根据头颅磁共振DWI序列分为前循环梗死组和后循环梗死组,按Giang提出的诊断标准检出基底动脉弯曲的患者,分析后循环脑梗死与基底动脉弯曲的关系,采用Logistic回归方法分析后循环脑梗死的独立危险因素。结果共64例(20%)脑梗死患者诊断为基底动脉弯曲,其中前循环梗死组基底动脉弯曲者34例(16%),后循环梗死组30例(29%),两者比较差异有统计学意义(P<0.05);多因素Logistic回归分析显示,基底动脉弯曲、既往短暂性脑缺血(TIA)病史、高同型半胱氨酸血症是后循环脑梗死的独立危险因素。结论基底动脉弯曲与后循环脑梗死的发生密切相关,基底动脉弯曲、既往TIA病史、高同型半胱氨酸血症是后循环脑梗死的独立危险因素。
Objective To investigate the relationship between posterior circulation cerebral infarction and basilar artery curvature and to analyze the related risk factors affecting posterior circulation cerebral infarction. Methods A total of 314 patients with cerebral infarction were retrospectively analyzed. Patients were divided into anterior circulation infarction group and posterior circulation infarction group according to DWI sequence of head MRI. Patients with basilar artery curvature were detected according to diagnostic criteria proposed by Giang. The relationship between posterior circulation cerebral infarction and basilar artery Bending relationship, using Logistic regression analysis of independent risk factors for recurrent cerebral infarction. Results A total of 64 cases (20%) of patients with cerebral infarction were diagnosed as basilar artery aneurysm, including 34 cases (16%) of basilar artery anterior curve and 30 cases of posterior circulation infarction group (29%), the difference was statistically (P <0.05). Multivariate Logistic regression analysis showed that basilar artery curvature, previous history of transient ischemic attack (TIA) and hyperhomocysteinemia were independent risk factors for posterior circulation cerebral infarction. Conclusions The basilar artery curvature is closely related to the occurrence of posterior circulation cerebral infarction. The curvature of the basilar artery, the history of previous TIA, and hyperhomocysteinemia are independent risk factors for posterior circulation cerebral infarction.