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目的探讨3.0 T磁共振动态增强对乳腺癌早期诊断的价值。方法回顾性分析2011年9月至2013年1月四川省人民医院收治的32例乳腺癌患者的MRI资料,分析病灶MRI信号、形态、邻近结构改变、强化方式及时间-信号强度曲线指标。结果本组32例T1W1、T2W1图像分别是低信号、低信号或混杂高信号;22例(68.8%)肿块呈现不规则,10例(31.3%)呈类圆形状;边缘有“毛刺征”者25例(78.1%),累及Cooper韧带者18例(56.3%),病灶可见砂粒样钙化者17例(53.1%),累及局部皮肤导致增厚者14例(43.8%),另乳头塌陷者6例(18.8%);所有病灶均不均匀强化,其中24个呈环形强化,8个见对比剂填充征;22个病灶呈Ⅲ型曲线(为快进快出型),9个病灶呈Ⅱ型曲线(为平台型),1个呈Ⅰ型曲线(为缓慢上升型)。结论磁共振动态增强时间-信号强度曲线结合肿瘤环行强化特点及毛刺征改变,进行多参数综合评估,可作为诊断乳腺癌的重要参考因素,有助于乳腺癌的早期诊断。
Objective To investigate the value of 3.0 T MRI in the early diagnosis of breast cancer. Methods The MRI data of 32 breast cancer patients who were treated in Sichuan Provincial People’s Hospital from September 2011 to January 2013 were retrospectively analyzed. MRI signals, morphological changes, adjacent structure changes, enhancement methods and time-signal intensity curve indexes were analyzed. Results Twenty-two cases of T1W1 and T2W1 images were low signal, low signal or mixed high signal respectively. Twenty-two patients (68.8%) showed irregular shape and 10 (31.3% (78.1%), 18 (56.3%) with Cooper ligament involvement, 17 (53.1%) with calcified calcification, 14 (43.8%) with local skin involvement, (18.8%). All of the lesions were nonuniformly enhanced. Among them, 24 showed ring-shaped enhancement and 8 showed contrast-filling. Twenty-two lesions showed type Ⅲ curve (fast forward and rapid exit) Type II curves (for the platform type), a curve was type Ⅰ (slow rise). Conclusion The combination of dynamic enhancement of time-signal intensity of magnetic resonance imaging (MRI) and enhancement of tumor circulation and the change of burr sign can be used as an important reference factor in the diagnosis of breast cancer and contribute to the early diagnosis of breast cancer.